Fruit is important in SCD
Bacteria causing infections
on human tissues have an affinity to bind to a certain sugar,
mannose, on the cell membranes of tissue. D-mannose is
a monosaccharide sugar found naturally in fruits and actually
is similar to glucose EXCEPT in its three-dimensional form (stereochemistry).
Although no one has done any research on its function, re
its presence in the intestine other than to indicate that it is involved
in immunological reactions,
there are reports on its therapeutic effect in the urinary tract where
cranberry juice (containing
much D-mannose)has a beneficial action in urinary tract infections.
It is very possible that in intestinal infections, the d-mannose in fruit
competes with the
on the cells in the
gut and provides competition which would allow the infectious
bacteria to leave their binding sites on the gut and attach to the
in fruit and,
thereby, have a beneficient effect in lessening the infection.
Bacteria that are involved
with gut pathology have been studied in ways that show how they initiate
a response by the immune system. In
most of these articles, there is the interaction of bacterial
cell walls and their ability to bind to cells of the urinary
tract and other mucosal cells (also the surface of the gut) through
D-mannose receptors. It is referred to as lectin binding to
D-mannose. The reason that cranberry juice has been used for urinary
because the bacteria causing the infections (E. coli where it should
not be in the urinary tract but this would apply to many other
bacterial species) is to "make" the bacteria adhere to the D-mannose
in cranberry juice and let go of the tissue
in the urinary tract or elsewhere.
D- Mannose is present in
fruit and altho it may be there is lesser amounts than the monosaccharides,
glucose and fructose, IT IS PRESENT.
In addition to its natural occurrence in the cells lining the
epithelial tract, the sugar D-mannose is also found in relatively large
in fruit such as peaches, pineapple, apples, oranges, and certain berries,
like cranberries and blueberries.
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